Effects of Matrix pH on Spontaneous Transient Depolarization and Reactive Oxygen Species Production in Mitochondria

Reactive oxygen species (ROS) oxidize surrounding molecules and thus impair their functions. Since mitochondria are a major source of ROS, suppression of ROS overproduction in the mitochondria is important for cells. Spontaneous transient depolarization of individual mitochondria is a physiological...

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Bibliographic Details
Main Authors: Jannatul Aklima, Takumi Onojima, Sawako Kimura, Kanji Umiuchi, Takahiro Shibata, Yusho Kuraoka, Yoshiki Oie, Yoshiki Suganuma, Yoshihiro Ohta
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.692776/full