Danthron ameliorates obesity and MAFLD through activating the interplay between PPARα/RXRα heterodimer and adiponectin receptor 2

Danthron ameliorates obesity and MAFLD through activating the interplay between PPARα/RXRα heterodimer and adiponectin receptor 2

Obesity and associated metabolic associated fatty liver diseases (MAFLD) are strongly associated with dysfunction of glucose and lipid metabolism. AMPKα and PPARα are key regulators in the lipid and glucose homeostasis, indicating that novel agents to activate them are promising therapeutic approach...

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Bibliographic Details
Main Authors: Chuanrui Ma, Zhongyan Wang, Ronglin Xia, Lingling Wei, Chao Zhang, Jing Zhang, Linna Zhao, Han Wu, Lin Kang, Shu Yang
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Danthron
Obesity
Hepatic steatosis
AdipoR2
AMPKα
PPARα
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221001293

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http://www.sciencedirect.com/science/article/pii/S0753332221001293

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