Identification of miR-26a as a target gene of bile acid receptor GPBAR-1/TGR5.

GPBAR1/TGR5 is a G protein-coupled receptor of bile acids. TGR5 is known to regulate the BA homeostasis and energy metabolism. Recent studies highlight an important role of TGR5 in alleviating obesity and improving glucose regulation, however, the mechanism of which is still unclear. Here we report...

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Bibliographic Details
Main Authors: Xiaosong Chen, Haixia Xu, Lili Ding, Guiyu Lou, Yan Liu, Yalan Yao, Liangwan Chen, Wendong Huang, Xianghui Fu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4481113?pdf=render