Sildenafil dosed concomitantly with bosentan for adult pulmonary arterial hypertension in a randomized controlled trial

Sildenafil dosed concomitantly with bosentan for adult pulmonary arterial hypertension in a randomized controlled trial

Abstract Background Few controlled clinical trials exist to support oral combination therapy in pulmonary arterial hypertension (PAH). Methods Patients with PAH (idiopathic [IPAH] or associated with connective tissue disease [APAH-CTD]) taking bosentan (62.5 or 125 mg twice daily at a stable dose fo...

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Bibliographic Details
Main Authors: Carmine Dario Vizza, Pavel Jansa, Simon Teal, Theresa Dombi, Duo Zhou
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Cardiovascular Disorders
Subjects:
Sildenafil - Bosentan - pulmonary hypertension - randomized controlled trial -exercise test
Combination therapy
Online Access:http://link.springer.com/article/10.1186/s12872-017-0674-3

Internet

http://link.springer.com/article/10.1186/s12872-017-0674-3

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