Regulation of terminal hypertrophic chondrocyte differentiation in Prmt5 mutant mice modeling infantile idiopathic scoliosis

Idiopathic scoliosis (IS) is the most common type of musculoskeletal defect affecting children worldwide, and is classified by age of onset, location and degree of spine curvature. Although rare, IS with onset during infancy is the more severe and rapidly progressive form of the disease, associated...

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Bibliographic Details
Main Authors: Zhaoyang Liu, Janani Ramachandran, Steven A. Vokes, Ryan S. Gray
Format: Article
Language:English
Published: The Company of Biologists 2019-12-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/12/12/dmm041251