Analysis of the interferon gamma (rs2430561, +874T/A) functional gene variant in relation to the presence of cardiovascular events in rheumatoid arthritis.

Analysis of the interferon gamma (rs2430561, +874T/A) functional gene variant in relation to the presence of cardiovascular events in rheumatoid arthritis.

OBJECTIVE: Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased cardiovascular (CV) morbidity and mortality. Since interferon-gamma (IFN-γ) has a direct effect on inflammation, in this study we assessed the potential association of the IFNG functional gene variant rs...

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Bibliographic Details
Main Authors: Mercedes García-Bermúdez, Raquel López-Mejías, Carlos González-Juanatey, Alfonso Corrales, Gema Robledo, Santos Castañeda, José A Miranda-Filloy, Ricardo Blanco, Benjamín Fernández-Gutiérrez, Alejandro Balsa, Isidoro González-Alvaro, Carmen Gómez-Vaquero, Javier Llorca, Javier Martín, Miguel A González-Gay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3471910?pdf=render

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http://europepmc.org/articles/PMC3471910?pdf=render

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