Impact of Mesenchymal Stromal Cells and Their Extracellular Vesicles in a Rat Model of Kidney Rejection

Impact of Mesenchymal Stromal Cells and Their Extracellular Vesicles in a Rat Model of Kidney Rejection

BackgroundMesenchymal stromal cells (MSCs) from different sources possess great therapeutic potential due to their immunomodulatory properties associated with allograft tolerance. However, a crucial role in this activity resides in extracellular vesicles (EVs) and signaling molecules secreted by cel...

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Bibliographic Details
Main Authors: Maria Jose Ramirez-Bajo, Jordi Rovira, Marta Lazo-Rodriguez, Elisenda Banon-Maneus, Valeria Tubita, Daniel Moya-Rull, Natalia Hierro-Garcia, Pedro Ventura-Aguiar, Federico Oppenheimer, Josep M. Campistol, Fritz Diekmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
bone marrow
adipose tissue
mesenchymal stromal cells
extracellular vesicles
kidney transplantation
immunomodulation
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00010/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00010/full

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