AP-1 as a Regulator of MMP-13 in the Stromal Cell of Giant Cell Tumor of Bone
Matrix-metalloproteinase-13 (MMP-13) has been shown to be an important protease in inflammatory and neoplastic conditions of the skeletal system. In particular, the stromal cells of giant cell tumor of bone (GCT) express very high levels of MMP-13 in response to the cytokine-rich environment of the...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2011-01-01
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Series: | Biochemistry Research International |
Online Access: | http://dx.doi.org/10.1155/2011/164197 |