Inference of Intercellular Communications and Multilayer Gene-Regulations of Epithelial–Mesenchymal Transition From Single-Cell Transcriptomic Data

Inference of Intercellular Communications and Multilayer Gene-Regulations of Epithelial–Mesenchymal Transition From Single-Cell Transcriptomic Data

Epithelial-to-mesenchymal transition (EMT) plays an important role in many biological processes during development and cancer. The advent of single-cell transcriptome sequencing techniques allows the dissection of dynamical details underlying EMT with unprecedented resolution. Despite several single...

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Bibliographic Details
Main Authors: Yutong Sha, Shuxiong Wang, Federico Bocci, Peijie Zhou, Qing Nie
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Genetics
Subjects:
single-cell RNA sequencing
trajectory inference
gene regulatory network
cell fate decision
cell–cell communication
multi-scale analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.604585/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.604585/full

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