Hypoxia increases adipogenesis and affects adipocytokine production in orbital fibroblasts–a possible explanation of the link between smoking and Graves’ ophthalmopathy

<b>AIM:</b> To assess the effects of hypoxia on human orbital fibroblasts (OF) on adipogenesis and adipocytokine production.<b>METHODS:</b>Human OF were derived from tissues obtained from patients with Graves’ ophthalmopathy (GO) and from patients without known thyroid diseas...

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Bibliographic Details
Main Authors: Chiaw Ling Chng, Oi Fah Lai, Charmaine Sze-Min Chew, Yu Pei Peh, Stephanie Man-Chung Fook-Chong, Lay Leng Seah, Daphne Hsu-Chin Khoo
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2014-06-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067649/