Hypoxia increases adipogenesis and affects adipocytokine production in orbital fibroblasts–a possible explanation of the link between smoking and Graves’ ophthalmopathy

Hypoxia increases adipogenesis and affects adipocytokine production in orbital fibroblasts–a possible explanation of the link between smoking and Graves’ ophthalmopathy

<b>AIM:</b> To assess the effects of hypoxia on human orbital fibroblasts (OF) on adipogenesis and adipocytokine production.<b>METHODS:</b>Human OF were derived from tissues obtained from patients with Graves’ ophthalmopathy (GO) and from patients without known thyroid diseas...

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Bibliographic Details
Main Authors: Chiaw Ling Chng, Oi Fah Lai, Charmaine Sze-Min Chew, Yu Pei Peh, Stephanie Man-Chung Fook-Chong, Lay Leng Seah, Daphne Hsu-Chin Khoo
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2014-06-01
Series:International Journal of Ophthalmology
Subjects:
hypoxia
smoking
Graves’ ophthalmopathy
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067649/

Internet

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067649/

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