May antidepressant drugs worsen the conditions they are supposed to treat? The clinical foundations of the oppositional model of tolerance
In recent years there has been a considerable debate on antidepressant drugs. Continued drug treatment with antidepressant medications may stimulate processes that run counter to the initial acute effects of a drug. The oppositional model of tolerance may explain loss of treatment efficacy during ma...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2020-10-01
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| Series: | Therapeutic Advances in Psychopharmacology |
| Online Access: | https://doi.org/10.1177/2045125320970325 |