BCL2L10 Is Overexpressed in Melanoma Downstream of STAT3 and Promotes Cisplatin and ABT-737 Resistance

BCL2L10 Is Overexpressed in Melanoma Downstream of STAT3 and Promotes Cisplatin and ABT-737 Resistance

The anti-apoptotic proteins from the Bcl-2 family are important therapeutic targets since they convey resistance to anticancer regimens. Despite the suspected functional redundancy among the six proteins of this subfamily, both basic studies and therapeutic approaches have focused mainly on BCL2, Bc...

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Bibliographic Details
Main Authors: María Josefina Quezada, María Elisa Picco, María Belén Villanueva, María Victoria Castro, Gastón Barbero, Natalia Brenda Fernández, Edith Illescas, Pablo Lopez-Bergami
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
BCL2L10
STAT3
melanoma
cytotoxicity
survival
ABT-737
Online Access:https://www.mdpi.com/2072-6694/13/1/78

Internet

https://www.mdpi.com/2072-6694/13/1/78

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