Linear ion-trap MSn with high-resolution MS reveals structural diversity of 1-O-acylceramide family in mouse epidermis

Linear ion-trap MSn with high-resolution MS reveals structural diversity of 1-O-acylceramide family in mouse epidermis

1-O-acylceramide is a new class of epidermal cer­amide (Cer) found in humans and mice. Here, we report an ESI linear ion-trap (LIT) multiple-stage MS (MSn) approach with high resolution toward structural characterization of this lipid family isolated from mice. Molecular species desorbed as the [M +...

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Bibliographic Details
Main Authors: Meei-Hua Lin, Jeffrey H. Miner, John Turk, Fong-Fu Hsu
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Journal of Lipid Research
Subjects:
skin ceramide
lipidomics
multiple-stage tandem mass spectrometry
electrospray ionization
higher collision energy dissociation
sphingolipid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520338542

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http://www.sciencedirect.com/science/article/pii/S0022227520338542

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