A toxin-antitoxin module in Bacillus subtilis can both mitigate and amplify effects of lethal stress.

Bacterial type-2 (protein-protein) toxin-antitoxin (TA) modules are two-gene operons that are thought to participate in the response to stress. Previous work with Escherichia coli has led to a debate in which some investigators conclude that the modules protect from stress, while others argue that t...

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Bibliographic Details
Main Authors: Xiangli Wu, Xiuhong Wang, Karl Drlica, Xilin Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3163665?pdf=render