Selective degeneration of septal and hippocampal GABAergic neurons in a mouse model of amyloidosis and tauopathy

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by brain accumulation of amyloid-β peptide and neurofibrillary tangles, which are believed to initiate a pathological cascade that results in progressive impairment of cognitive functions and eventual neuronal death. To obta...

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Bibliographic Details
Main Authors: Desirée Loreth, Laurence Ozmen, Florent G. Revel, Frédéric Knoflach, Philine Wetzel, Michael Frotscher, Friedrich Metzger, Oliver Kretz
Format: Article
Language:English
Published: Elsevier 2012-07-01
Series:Neurobiology of Disease
Subjects:
Tau
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112000824