Mechanisms of Reactivation and Its Interaction with

The telomerase reverse transcriptase (TERT) gene, which is repressed in most differentiated human cells, can be reactivated by somatic TERT alterations and epigenetic modulations. Moreover, the recruitment, accessibility, and binding of transcription factors also affect the regulation of TERT expres...

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Bibliographic Details
Main Authors: Young Shin Song, Young Joo Park
Format: Article
Language:English
Published: Academya Publishing Co. 2020-09-01
Series:Endocrinology and Metabolism
Subjects:
Online Access:http://www.e-enm.org/upload/pdf/enm-2020-304.pdf