Electrotonic signals along intracellular membranes may interconnect dendritic spines and nucleus.
Synapses on dendritic spines of pyramidal neurons show a remarkable ability to induce phosphorylation of transcription factors at the nuclear level with a short latency, incompatible with a diffusion process from the dendritic spines to the nucleus. To account for these findings, we formulated a nov...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-03-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2266990?pdf=render |