Electrotonic signals along intracellular membranes may interconnect dendritic spines and nucleus.

Synapses on dendritic spines of pyramidal neurons show a remarkable ability to induce phosphorylation of transcription factors at the nuclear level with a short latency, incompatible with a diffusion process from the dendritic spines to the nucleus. To account for these findings, we formulated a nov...

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Bibliographic Details
Main Authors: Isaac Shemer, Björn Brinne, Jesper Tegnér, Sten Grillner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2266990?pdf=render