Impact of serum amyloid A on high density lipoprotein composition and levels

Serum amyloid A (SAA) is an acute-phase protein mainly associated with HDL. To study the role of SAA in mediating changes in HDL composition and metabolism during inflammation, we generated mice in which the two major acute-phase SAA isoforms, SAA1.1 and SAA2.1, were deleted [SAA knockout (SAAKO) mi...

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Bibliographic Details
Main Authors: Maria C. de Beer, Nancy R. Webb, Joanne M. Wroblewski, Victoria P. Noffsinger, Debra L. Rateri, Ailing Ji, Deneys R. van der Westhuyzen, Frederick C. de Beer
Format: Article
Language:English
Published: Elsevier 2010-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520409459