The predicted ABC transporter AbcEDCBA is required for type IV secretion system expression and lysosomal evasion by Brucella ovis.

Brucella ovis is a major cause of reproductive failure in rams and it is one of the few well-described Brucella species that is not zoonotic. Previous work showed that a B. ovis mutant lacking a species-specific ABC transporter (ΔabcBA) was attenuated in mice and was unable to survive in macrophages...

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Bibliographic Details
Main Authors: Teane M A Silva, Juliana P S Mol, Maria G Winter, Vidya Atluri, Mariana N Xavier, Simone F Pires, Tatiane A Paixão, Hélida M Andrade, Renato L Santos, Renee M Tsolis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0114532