The effect of osteoporosis treatments on fatigue properties of cortical bone tissue

The effect of osteoporosis treatments on fatigue properties of cortical bone tissue

Bisphosphonates are commonly prescribed for treatment of osteoporosis. Long-term use of bisphosphonates has been correlated to atypical femoral fractures (AFFs). AFFs arise from fatigue damage to bone tissue that cannot be repaired due to pharmacologic treatments. Despite fatigue being the primary d...

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Bibliographic Details
Main Authors: Garry R. Brock, Julia T. Chen, Anthony R. Ingraffea, Jennifer MacLeay, G. Elizabeth Pluhar, Adele L. Boskey, Marjolein C.H. van der Meulen
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Bone Reports
Subjects:
Biomechanics
Osteoporosis
Fatigue testing
Bisphosphonate
Raloxifene
Metabolic acidosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187214000059

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http://www.sciencedirect.com/science/article/pii/S2352187214000059

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