Individual variability in behavior and functional networks predicts vulnerability using an animal model of PTSD

How do individual differences affect vulnerability to developing post-traumatic stress disorder (PTSD)? Here, using longitudinal testing in a rat model of PTSD, the authors show patterns of pre-trauma brain connectivity and behaviors that predict PTSD-like responses to trauma exposure.

Bibliographic Details
Main Authors: David Dopfel, Pablo D. Perez, Alexander Verbitsky, Hector Bravo-Rivera, Yuncong Ma, Gregory J. Quirk, Nanyin Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2019-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09926-z