Harmful effects of the azathioprine metabolite 6-mercaptopurine in vascular cells: induction of mineralization.

Vascular mineralization contributes to the high cardiovascular morbidity and mortality in patients who suffer from chronic kidney disease and in individuals who have undergone solid organ transplantation. The immunosuppressive regimen used to treat these patients appears to have an impact on vascula...

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Bibliographic Details
Main Authors: Jasmin Prüfer, Mirjam Schuchardt, Markus Tölle, Nicole Prüfer, Matthias Höhne, Walter Zidek, Markus van der Giet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4100760?pdf=render