Nuclear Lipid Microdomains Regulate Daunorubicin Resistance in Hepatoma Cells

Nuclear Lipid Microdomains Regulate Daunorubicin Resistance in Hepatoma Cells

Daunorubicin is an anticancer drug, and cholesterol is involved in cancer progression, but their relationship has not been defined. In this study, we developed a novel experimental model that utilizes daunorubicin, cholesterol, and daunorubicin plus cholesterol in the same cells (H35) to search for...

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Bibliographic Details
Main Authors: Michela Codini, Carmela Conte, Samuela Cataldi, Cataldo Arcuri, Andrea Lazzarini, Maria Rachele Ceccarini, Federica Patria, Alessandro Floridi, Carmen Mecca, Francesco Saverio Ambesi-Impiombato, Tommaso Beccari, Francesco Curcio, Elisabetta Albi
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
sphingomyelin
cholesterol
nuclear membrane
nuclear lipid microdomains
daunorubicin
Online Access:https://www.mdpi.com/1422-0067/19/11/3424

Internet

https://www.mdpi.com/1422-0067/19/11/3424

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