Complement lysis activity in autologous plasma is associated with lower viral loads during the acute phase of HIV-1 infection.

<h4>Background</h4>To explore the possibility that antibody-mediated complement lysis contributes to viremia control in HIV-1 infection, we measured the activity of patient plasma in mediating complement lysis of autologous primary virus.<h4>Methods and findings</h4>Sera from...

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Bibliographic Details
Main Authors: Michael Huber, Marek Fischer, Benjamin Misselwitz, Amapola Manrique, Herbert Kuster, Barbara Niederöst, Rainer Weber, Viktor von Wyl, Huldrych F Günthard, Alexandra Trkola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-11-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.0030441