Thrombin regulation of synaptic transmission: Implications for seizure onset

Seizures are a common outcome of cerebrovascular events as well as of traumatic brain injuries. Thrombin, a protease-activated receptor (PAR) agonist, has been implicated in the onset of seizures in these settings, yet its mode of action is not entirely clear. In this study, the effect of thrombin a...

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Bibliographic Details
Main Authors: Nicola Maggio, Carlo Cavaliere, Michele Papa, Ilan Blatt, Joab Chapman, Menahem Segal
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112003452