Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro

Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro

<p>Abstract</p> <p>Background</p> <p>Signal transducer and activator of transcription 3 (Stat3) is a member of the Janus-activated kinase(Jak)/Stat signaling pathway. Abnormal activation of Stat3 plays a critical role in metastasis and invasion in varieties of human tum...

Full description

Bibliographic Details
Main Authors: Cao Jun, Huang Kejian, Jiang Tao, Yang Guang, Huang Chen, Qiu Zhengjun
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/29/1/51

Internet

http://www.jeccr.com/content/29/1/51

Similar Items