Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model

Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model

Abstract Background Enterovirus 71 (EV71 or EV-A71) was first identified in California about half a century ago. In recent years, outbreaks of EV-A71 were prevalent worldwide, including Taiwan, Malaysia, Singapore, Japan, and China. Between 2008 and 2011, China alone reported 1894 deaths associated...

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Bibliographic Details
Main Authors: An-Ting Liou, Chun-Che Liao, Shu-Fan Chou, Ya-Shu Chang, Chih-Shin Chang, Chiaho Shih
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Biomedical Science
Subjects:
EV-A71
enterovirus
hypoxia
White-Jade muscle
therapy
mouse model
Online Access:http://link.springer.com/article/10.1186/s12929-019-0585-y

Internet

http://link.springer.com/article/10.1186/s12929-019-0585-y

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