Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model
Abstract Background Enterovirus 71 (EV71 or EV-A71) was first identified in California about half a century ago. In recent years, outbreaks of EV-A71 were prevalent worldwide, including Taiwan, Malaysia, Singapore, Japan, and China. Between 2008 and 2011, China alone reported 1894 deaths associated...
Main Authors: | An-Ting Liou, Chun-Che Liao, Shu-Fan Chou, Ya-Shu Chang, Chih-Shin Chang, Chiaho Shih |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-11-01
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Series: | Journal of Biomedical Science |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12929-019-0585-y |
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