Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis

The proneural transcription factor Ascl1 coordinates gene expression in both proliferating and differentiating progenitors along the neuronal lineage. Here, we used a cellular model of neurogenesis to investigate how Ascl1 interacts with the chromatin landscape to regulate gene expression when promo...

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Bibliographic Details
Main Authors: Alexandre A.S.F. Raposo, Francisca F. Vasconcelos, Daniela Drechsel, Corentine Marie, Caroline Johnston, Dirk Dolle, Angela Bithell, Sébastien Gillotin, Debbie L.C. van den Berg, Laurence Ettwiller, Paul Flicek, Gregory E. Crawford, Carlos M. Parras, Benedikt Berninger, Noel J. Buckley, François Guillemot, Diogo S. Castro
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715001710