Distinct Roles for Sialoside and Protein Receptors in Coronavirus Infection
CoVs can transmit from animals to humans to cause serious disease. This zoonotic transmission uses spike proteins, which bind CoVs to cells with two receptor-binding domains. Here, we identified the roles for the two binding processes in the CoV infection process. Binding to sialic acids promoted in...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2020-02-01
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Series: | mBio |
Subjects: | |
Online Access: | https://doi.org/10.1128/mBio.02764-19 |