Gene profiling of postnatal Mfrprd6 mutant eyes reveals differential accumulation of Prss56, visual cycle and phototransduction mRNAs.

Gene profiling of postnatal Mfrprd6 mutant eyes reveals differential accumulation of Prss56, visual cycle and phototransduction mRNAs.

Mutations in the membrane frizzled-related protein (MFRP/Mfrp) gene, specifically expressed in the retinal pigment epithelium (RPE) and ciliary body, cause nanophthalmia or posterior microphthalmia with retinitis pigmentosa in humans, and photoreceptor degeneration in mice. To better understand MFRP...

Full description

Bibliographic Details
Main Authors: Ramani Soundararajan, Jungyeon Won, Timothy M Stearns, Jeremy R Charette, Wanda L Hicks, Gayle B Collin, Jürgen K Naggert, Mark P Krebs, Patsy M Nishina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4214712?pdf=render

Internet

http://europepmc.org/articles/PMC4214712?pdf=render

Similar Items