Profiling of Oral Microbiota in Early Childhood Caries Using Single-Molecule Real-Time Sequencing

Profiling of Oral Microbiota in Early Childhood Caries Using Single-Molecule Real-Time Sequencing

Background: Alterations of oral microbiota are the main cause of the progression of caries. The goal of this study was to characterize the oral microbiota in childhood caries based on single-molecule real-time sequencing.Methods: A total of 21 preschoolers, aged 3–5 years old with severe early child...

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Bibliographic Details
Main Authors: Yuan Wang, Jie Zhang, Xi Chen, Wen Jiang, Sa Wang, Lei Xu, Yan Tu, Pei Zheng, Ying Wang, Xiaolong Lin, Hui Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Microbiology
Subjects:
caries
oral microbiome
PacBio RS II system
sequencing
healthy
NCT02341352. Registered 13 January 2015. retrospectively registered.
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02244/full

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http://journal.frontiersin.org/article/10.3389/fmicb.2017.02244/full

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