Trained immunity modulates inflammation-induced fibrosis

Innate immune cells can be trained by some stimuli or pathogen exposures to be metabolically and epigenetically altered such that they have different responses to subsequent exposures. Here the authors show that low-dose LPS trained macrophages and BCG-trained macrophages have opposing effects on fi...

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Bibliographic Details
Main Authors: Mohamed Jeljeli, Luiza Gama Coelho Riccio, Ludivine Doridot, Charlotte Chêne, Carole Nicco, Sandrine Chouzenoux, Quentin Deletang, Yannick Allanore, Niloufar Kavian, Frédéric Batteux
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13636-x