Prognostic significance of CD8+ T-cells density in stage III colorectal cancer depends on SDF-1 expression

Abstract Since colorectal cancer (CRC) remains one of the most common malignancies, a tremendous amount of studies keep taking place in this field. Over the past 25 years, a notable part of the scientific community has focused on the association between the immune system and colorectal cancer. A var...

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Bibliographic Details
Main Authors: Alexandros Lalos, Ali Tülek, Nadia Tosti, Robert Mechera, Alexander Wilhelm, Savas Soysal, Silvio Daester, Venkatesh Kancherla, Benjamin Weixler, Giulio C. Spagnoli, Serenella Eppenberger-Castori, Luigi Terracciano, Salvatore Piscuoglio, Markus von Flüe, Alberto Posabella, Raoul A. Droeser
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80382-2