53BP1 Accumulation in Circulating Tumor Cells Identifies Chemotherapy-Responsive Metastatic Breast Cancer Patients

53BP1 Accumulation in Circulating Tumor Cells Identifies Chemotherapy-Responsive Metastatic Breast Cancer Patients

Evidence suggests that the DNA end-binding protein p53-binding protein 1 (53BP1) is down-regulated in subsets of breast cancer. Circulating tumor cells (CTCs) provide accessible “biopsy material” to track cell traits and functions and their alterations during treatment. Here, we prospectively monito...

Full description

Bibliographic Details
Main Authors: Fabienne Schochter, Kim Werner, Cäcilia Köstler, Anke Faul, Marie Tzschaschel, Barbara Alberter, Volkmar Müller, Hans Neubauer, Tanja Fehm, Thomas W.P. Friedl, Bernhard Polzer, Wolfgang Janni, Brigitte Rack, Lisa Wiesmüller
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
metastatic breast cancer
circulating tumor cells
triple-negative
hormone receptor
Eribulin
predictive biomarker
Online Access:https://www.mdpi.com/2072-6694/12/4/930

Internet

https://www.mdpi.com/2072-6694/12/4/930

Similar Items