All-Trans Retinoic Acid Attenuates Fibrotic Processes by Downregulating TGF-β1/Smad3 in Early Diabetic Nephropathy
Diabetic nephropathy (DN) involves damage associated to hyperglycemia and oxidative stress. Renal fibrosis is a major pathologic feature of DN. The aim of this study was to evaluate anti-fibrogenic and renoprotective effects of all-trans retinoic acid (ATRA) in isolated glomeruli and proximal tubule...
Main Authors: | Edith Sierra-Mondragon, Rafael Rodríguez-Muñoz, Carmen Namorado-Tonix, Eduardo Molina-Jijon, Daniel Romero-Trejo, Jose Pedraza-Chaverri, Jose L. Reyes |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-09-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/9/10/525 |
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