Neutrophil extracellular traps contribute to the pathogenesis of leprosy type 2 reactions.

Neutrophil extracellular traps contribute to the pathogenesis of leprosy type 2 reactions.

Up to 50% of patients with the multibacillary form of leprosy are expected to develop acute systemic inflammatory episodes known as type 2 reactions (T2R), thus aggravating their clinical status. Thalidomide rapidly improves T2R symptoms. But, due to its restricted use worldwide, novel alternative t...

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Bibliographic Details
Main Authors: Camila Oliveira da Silva, André Alves Dias, José Augusto da Costa Nery, Alice de Miranda Machado, Helen Ferreira, Thais Fernanda Rodrigues, João Pedro Sousa Santos, Natalia Rocha Nadaes, Euzenir Nunes Sarno, Elvira Maria Saraiva, Verônica Schmitz, Maria Cristina Vidal Pessolani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007368

Internet

https://doi.org/10.1371/journal.pntd.0007368

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