Possible role of TCF7L2 in the pathogenesis of type 2 diabetes mellitus

Possible role of TCF7L2 in the pathogenesis of type 2 diabetes mellitus

With people's changing life style and dietary habits, the prevalence of type 2 diabetes mellitus (T2DM) has become much more serious than ever before. T2DM is a polygenic metabolic disorder, resulting from the interaction of genetic and various environmental factors. Among all the T2DM related...

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Bibliographic Details
Main Authors: Zhi-qiu Huang, Yao-qi Liao, Run-ze Huang, Jin-peng Chen, Hui-lin Sun
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
T2DM
TCF7L2
genetic mutation
Wnt signaling pathway
β-cell apoptosis
proinsulin conversion
β-cell responsiveness
Online Access:http://dx.doi.org/10.1080/13102818.2018.1438211

Internet

http://dx.doi.org/10.1080/13102818.2018.1438211

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