Circulating free DNA as biomarker and source for mutation detection in metastatic colorectal cancer.

BACKGROUND:Circulating cell-free DNA (cfDNA) in plasma has shown potential as biomarker in various cancers and could become an importance source for tumour mutation detection. The objectives of our study were to establish a normal range of cfDNA in a cohort of healthy individuals and to compare this...

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Bibliographic Details
Main Authors: Karen Lise Garm Spindler, Niels Pallisgaard, Rikke Fredslund Andersen, Ivan Brandslund, Anders Jakobsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395277?pdf=render