Impact of isoniazid resistance-conferring mutations on the clinical presentation of isoniazid monoresistant tuberculosis.

Specific isoniazid (INH) resistance conferring mutations have been shown to impact the likelihood of tuberculosis (TB) transmission. However, their role in the clinical presentation and outcomes of TB has not been evaluated.We included all cases of culture-confirmed, INH monoresistant tuberculosis r...

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Bibliographic Details
Main Authors: Raymund Dantes, John Metcalfe, Elizabeth Kim, Midori Kato-Maeda, Philip C Hopewell, Masae Kawamura, Payam Nahid, Adithya Cattamanchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3359338?pdf=render