PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes.

Phosphoinositide 3-kinases (PI3Ks) regulate numerous physiological processes including some aspects of cardiac function. Although regulation of cardiac contraction by individual PI3K isoforms has been studied, little is known about the cardiac consequences of downregulating multiple PI3Ks concurrent...

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Bibliographic Details
Main Authors: Chia-Yen C Wu, Zhiheng Jia, Wei Wang, Lisa M Ballou, Ya-Ping Jiang, Biyi Chen, Richard T Mathias, Ira S Cohen, Long-Sheng Song, Emilia Entcheva, Richard Z Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3166327?pdf=render