Glioma Revisited: From Neurogenesis and Cancer Stem Cells to the Epigenetic Regulation of the Niche

Gliomas are the most incident brain tumor in adults. This malignancy has very low survival rates, even when combining radio- and chemotherapy. Among the gliomas, glioblastoma multiforme (GBM) is the most common and aggressive type, and patients frequently relapse or become refractory to conventional...

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Bibliographic Details
Main Authors: Felipe de Almeida Sassi, Algemir Lunardi Brunetto, Gilberto Schwartsmann, Rafael Roesler, Ana Lucia Abujamra
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2012/537861