C-Tb skin test to diagnose Mycobacterium tuberculosis infection in children and HIV-infected adults: A phase 3 trial.

BACKGROUND:C-Tb, an ESAT-6/CFP-10-based skin test, has similar sensitivity for active TB compared to tuberculin skin test (TST) and QuantiFERON-TB-Gold-In-Tube (QFT). However, data are limited in children and HIV-infected persons. METHODS:Asymptomatic South African contacts <5 years (n = 87; HIV-...

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Bibliographic Details
Main Authors: Henrik Aggerbeck, Morten Ruhwald, Søren T Hoff, Bettine Borregaard, Elizabeth Hellstrom, Mookho Malahleha, Mirna Siebert, Mashra Gani, Vincent Seopela, Andreas Diacon, Madeleine Lourens, Peter Andersen, Keertan Dheda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6152999?pdf=render