Degranulating mast cells in fibrotic regions of human tumors and evidence that mast cell heparin interferes with the growth of tumor cells through a mechanism involving fibroblasts

<p>Abstract</p> <p>Background</p> <p>The purpose of this study was to test the hypothesis that mast cells that are present in fibrotic regions of cancer can suppress the growth of tumor cells through an indirect mechanism involving peri-tumoral fibroblasts.</p> &l...

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Bibliographic Details
Main Authors: Kanakubo Emi, Samoszuk Michael, Chan John K
Format: Article
Language:English
Published: BMC 2005-09-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/5/121