The Intratumoral Heterogeneity Reflects the Intertumoral Subtypes of Glioblastoma Multiforme: A Regional Immunohistochemistry Analysis

The Intratumoral Heterogeneity Reflects the Intertumoral Subtypes of Glioblastoma Multiforme: A Regional Immunohistochemistry Analysis

Glioblastoma multiforme (GBM) is the most frequent and aggressive primary brain tumor in adults. Despite extensive therapy the prognosis for GBM patients remains poor and the extraordinary therapy resistance has been attributed to intertumoral heterogeneity of glioblastoma. Different prognostic rele...

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Bibliographic Details
Main Authors: Natalie Bergmann, Claire Delbridge, Jens Gempt, Annette Feuchtinger, Axel Walch, Lucas Schirmer, Wolfram Bunk, Thomas Aschenbrenner, Friederike Liesche-Starnecker, Jürgen Schlegel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Oncology
Subjects:
glioblastoma
histological subtypes
intratumoral heterogeneity
intertumoral heterogeneity
histological architecture
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00494/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00494/full

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