Targeted mutagenesis in a human-parasitic nematode.

Parasitic nematodes infect over 1 billion people worldwide and cause some of the most common neglected tropical diseases. Despite their prevalence, our understanding of the biology of parasitic nematodes has been limited by the lack of tools for genetic intervention. In particular, it has not yet be...

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Bibliographic Details
Main Authors: Spencer S Gang, Michelle L Castelletto, Astra S Bryant, Emily Yang, Nicholas Mancuso, Jacqueline B Lopez, Matteo Pellegrini, Elissa A Hallem
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006675