Tissue-resident memory T cells play a key role in the efficacy of cancer vaccines

Resident memory CD8+T cells (TRM) usually defined by the CD103 marker represent a new subset of long-lived memory T cells that remain in the tissues. We directly demonstrate their specific role in cancer vaccine-induced tumor regression. In human, they also seem to play a major role in tumor immunos...

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Bibliographic Details
Main Authors: C. Granier, C. Blanc, S. Karaki, T. Tran, H. Roussel, E. Tartour
Format: Article
Language:English
Published: Taylor & Francis Group 2017-11-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1358841