Tissue-resident memory T cells play a key role in the efficacy of cancer vaccines
Resident memory CD8+T cells (TRM) usually defined by the CD103 marker represent a new subset of long-lived memory T cells that remain in the tissues. We directly demonstrate their specific role in cancer vaccine-induced tumor regression. In human, they also seem to play a major role in tumor immunos...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2017-11-01
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| Series: | OncoImmunology |
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| Online Access: | http://dx.doi.org/10.1080/2162402X.2017.1358841 |
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doaj-438097838eae48c6b0bd07f878f6c4da |
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doaj-438097838eae48c6b0bd07f878f6c4da2020-11-25T03:01:12ZengTaylor & Francis GroupOncoImmunology2162-402X2017-11-0161110.1080/2162402X.2017.13588411358841Tissue-resident memory T cells play a key role in the efficacy of cancer vaccinesC. Granier0C. Blanc1S. Karaki2T. Tran3H. Roussel4E. Tartour5Université Paris Descartes Sorbonne Paris-CitéUniversité Paris Descartes Sorbonne Paris-CitéUniversité Paris Descartes Sorbonne Paris-CitéUniversité Paris Descartes Sorbonne Paris-CitéUniversité Paris Descartes Sorbonne Paris-CitéUniversité Paris Descartes Sorbonne Paris-CitéResident memory CD8+T cells (TRM) usually defined by the CD103 marker represent a new subset of long-lived memory T cells that remain in the tissues. We directly demonstrate their specific role in cancer vaccine-induced tumor regression. In human, they also seem to play a major role in tumor immunosurveillance.http://dx.doi.org/10.1080/2162402X.2017.1358841resident memory t cellcancer vaccinetumor microenvironmentroute of immunizationimmunosurveillance |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
C. Granier C. Blanc S. Karaki T. Tran H. Roussel E. Tartour |
| spellingShingle |
C. Granier C. Blanc S. Karaki T. Tran H. Roussel E. Tartour Tissue-resident memory T cells play a key role in the efficacy of cancer vaccines OncoImmunology resident memory t cell cancer vaccine tumor microenvironment route of immunization immunosurveillance |
| author_facet |
C. Granier C. Blanc S. Karaki T. Tran H. Roussel E. Tartour |
| author_sort |
C. Granier |
| title |
Tissue-resident memory T cells play a key role in the efficacy of cancer vaccines |
| title_short |
Tissue-resident memory T cells play a key role in the efficacy of cancer vaccines |
| title_full |
Tissue-resident memory T cells play a key role in the efficacy of cancer vaccines |
| title_fullStr |
Tissue-resident memory T cells play a key role in the efficacy of cancer vaccines |
| title_full_unstemmed |
Tissue-resident memory T cells play a key role in the efficacy of cancer vaccines |
| title_sort |
tissue-resident memory t cells play a key role in the efficacy of cancer vaccines |
| publisher |
Taylor & Francis Group |
| series |
OncoImmunology |
| issn |
2162-402X |
| publishDate |
2017-11-01 |
| description |
Resident memory CD8+T cells (TRM) usually defined by the CD103 marker represent a new subset of long-lived memory T cells that remain in the tissues. We directly demonstrate their specific role in cancer vaccine-induced tumor regression. In human, they also seem to play a major role in tumor immunosurveillance. |
| topic |
resident memory t cell cancer vaccine tumor microenvironment route of immunization immunosurveillance |
| url |
http://dx.doi.org/10.1080/2162402X.2017.1358841 |
| work_keys_str_mv |
AT cgranier tissueresidentmemorytcellsplayakeyroleintheefficacyofcancervaccines AT cblanc tissueresidentmemorytcellsplayakeyroleintheefficacyofcancervaccines AT skaraki tissueresidentmemorytcellsplayakeyroleintheefficacyofcancervaccines AT ttran tissueresidentmemorytcellsplayakeyroleintheefficacyofcancervaccines AT hroussel tissueresidentmemorytcellsplayakeyroleintheefficacyofcancervaccines AT etartour tissueresidentmemorytcellsplayakeyroleintheefficacyofcancervaccines |
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