Inhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas disease.

Inhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas disease.

We had formerly demonstrated that subjects chronically infected with Trypanosoma cruzi show impaired T cell responses closely linked with a process of T cell exhaustion. Recently, the expression of several inhibitory receptors has been associated with T cell dysfunction and exhaustion. In this study...

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Bibliographic Details
Main Authors: Rafael J Argüello, María C Albareda, María G Alvarez, Graciela Bertocchi, Alejandro H Armenti, Carlos Vigliano, Patricia C Meckert, Rick L Tarleton, Susana A Laucella
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3344843?pdf=render

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http://europepmc.org/articles/PMC3344843?pdf=render

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